UNITED STATES PHARMACOPEIAL CONVENTION INC -- 18500 DIAZEPAM 100 MG  -- 6505-00F052794
<pre>=====================  Product Identification  =====================

Product ID:18500 DIAZEPAM 100 MG
MSDS Date:11/20/1995
FSC:6505
NIIN:00F052794
=== Responsible Party ===
Company Name:UNITED STATES PHARMACOPEIAL CONVENTION INC
Address:12601 TWINBROOK PKWY
City:ROCKVILLE
State:MD
ZIP:20852-1717
Country:US
Info Phone Num:301-881-0666
Emergency Phone Num:301-881-0666
Preparer's Name:JEROME A HALPERIN
CAGE:14128
=== Contractor Identification ===
Company Name:UNITED STATES PHARMACOPEIAL CONVENTION INC
Address:12601 TWINBROOK PKWY
Box:City:ROCKVILLE
State:MD
ZIP:20852-1717
Country:US
Phone:301-881-0666
CAGE:14128

=============  Composition/Information on Ingredients  =============

Ingred Name:DIAZEPAM	     (IARC CARCINOGEN - GROUP 3)	*96-4*
CAS:439-14-5
RTECS #:DF1575000

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:ORAL LD50(RAT): 352 MG/KG
Routes of Entry: Inhalation:YES  Skin:NO  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:MAY CAUSE IRRITATION TO EYES, SKIN,
    RESPIRATORY TRACT, MUCOUS MEMBRANES. POSSIBLE HYPERSENSITIZATION &
    DEPENDENCE. INGESTION: MAY CAUSE IRRITATION. MATERIAL IS COMPLETELY
    ABSORBED FROM GI TRACT. DIAZE PAM HAS BEEN REPORTED TO INCREASE
    RISK OF CONGENITAL MALFORMATIONS WHEN USED DURING FIRST TRIMESTER
    OF PREGNANCY.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:IRRITATION, DROWSINESS, FATIGUE, DIZZINESS,
    MENTAL DEPRESSION, SLURRED SPEECH, CLUMSINESS, CONFUSION, DECREASED
    REFLEXES, SHAKINESS, SLOW HEARTBEAT, TROUBLED BREATHING, SEVERE
    WEAKNESS, STAGGERING, AL LERGIC REACTION.
Medical Cond Aggravated by Exposure:HYPERSENSITIVITY TO MATERIAL,
    GLAUCOMA, MYASTHENIA GRAVIS & HEART DISEASE.

=======================  First Aid Measures  =======================

First Aid:INHALATION: REMOVE TO FRESH AIR. EYES/SKIN: FLUSH W/COPIOUS
    QUANTITIES OF WATER. INGESTION: FLUSH MOUTH OUT W/WATER. PERSONS
    DEVELOPING SERIOUS HYPERSENSITIVITY REACTIONS MUST RECEIVE
    IMMEDIATE MEDICA L ATTENTION. GIVE CPR/OXYGEN IF NEEDED.OBTAIN
    MEDICAL ATTENTION IN ALL CASES.

=====================  Fire Fighting Measures  =====================

Extinguishing Media:WATER SPRAY, DRY CHEMICAL, CO2, FOAM AS APPROPRIATE
    FOR SURROUNDING FIRE & MATERIALS.
Fire Fighting Procedures:EVACUATE PERSONNEL TO SAFE AREA. WEAR SCBA &
    PROTECTIVE CLOTHING.
Unusual Fire/Explosion Hazard:THIS MATERIAL IS ASSUMED TO BE
    COMBUSTIBLE. EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

==================  Accidental Release Measures  ==================

Spill Release Procedures:WEAR APPROVED RESPIRATOR & CHEMICALLY
    COMPATIBLE GLOVES. VACUUM/SWEEP UP. AVOID DUST. PLACE MATERIAL IN
    APPROPRIATE CONTAINER FOR WASTE DISPOSAL. VENTILATE AREA & WASH
    SITE.

======================	Handling and Storage  ======================

Handling and Storage Precautions:STORE IN TIGHT, LIGHT-RESISTANT
    CONTAINERS AS DEFINED IN U.S. PHARMACOPEIA. USE W/ADEQUATE DUST
    CONTROL.
Other Precautions:AVOID CONTACT W/EYES, SKIN/CLOTHING. AVOID BREATHING
    DUST/MIST. DON'T PERMIT EATING, DRINKING/SMOKING NEAR MATERIAL.
    GROUND MECHANICAL EQUIPMENT IN CONTACT W/DRY MATERIAL TO DISSIPATE
    POTENTIAL BUILDU P OF STATIC ELECTRICITY.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:WEAR A NIOSH APPROVED RESPIRATOR.
Ventilation:LOCAL EXHAUST/MECHANICAL (GENERAL): RECOMMENDED.
Protective Gloves:RUBBER
Eye Protection:SAFETY GOGGLES
Other Protective Equipment:APPROPRIATE LABORATORY APPAREL
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE
    REUSE. WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
MELTING POINT: 267.8-275F. ALSO REPORTED AS 257F. THIS MATERIAL SHOULD
    BE HANDLED & STORED PER LABEL & OTHER INSTRUCTIONS TO ENSURE
    PRODUCT INTEGRITY. INDIVIDUALS WORKING W/CHEMICALS SHOULD CONSIDER
    A LL CHEMICALS TO BE POTENTIALLY HAZARDOUS EVEN IF THEIR INDIVIDUAL
    HAZARDS MAY BE UNCHARACTERIZED/UNKNOWN.

==================  Physical/Chemical Properties  ==================

Melt/Freeze Pt:M.P/F.P Text:(SEE SUPP)
Solubility in Water:INSOLUBLE
Appearance and Odor:OFF-WHITE TO YELLOW CRYSTALLINE POWDER
    W/PRACTICALLY NO ODOR.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
STRONG BASES, MINERAL ACID, OXIDIZING AGENTS.
Stability Condition to Avoid:HEAT, MOISTURE, AIR & LIGHT.
Hazardous Decomposition Products:WHEN HEATED TO DECOMPOSITION: NITROGEN
    OXIDES & CHLORINE.

====================  Disposal Considerations  ====================

Waste Disposal Methods:DISPOSE OF IAW/FEDERAL, STATE & LOCAL
    REGULATIONS.

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 This information is formulated for use by elements of the Department
 of Defense.  The United States of America in no manner whatsoever,
 expressly or implied, warrants this information to be accurate and
 disclaims all liability for its use.  Any person utilizing this
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